Adult Onset Still’s Disease Presenting with Acute Respiratory Distress Syndrome: Case Report and Review of the Literature

Anisha B. Dua*, 1, Augustine M. Manadan2, John P. Case2
1 University of Chicago Medical Center
2 Rush University Medical Center and John H. Stroger, Jr. Hospital of Cook County, USA

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© Dua et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the University of Chicago Medical Center, Department of Rheumatology, 5800 S. Maryland Ave, MC0930, Room #N005, Chicago, IL 60637, USA; Tel: 773-702-8702; E-mail:



Adult-onset Still’s disease (AOSD) is a systemic inflammatory disorder characterized by rash, leukocytosis, fevers, and arthralgias. Pulmonary involvement has been reported rarely in AOSD, but acute respiratory distress syndrome (ARDS) is extremely rare and potentially fatal and must be recognized as potential manifestation of underlying AOSD.


We present a case of AOSD manifested by ARDS and review the previously reported cases in Medline/Pub med.


Including this case, 19 cases of AOSD complicated with ARDS have been reported in the literature.


It is important to recognize ARDS as a manifestation of AOSD so that proper diagnostic and therapeutic management can be initiated promptly.

Keywords: : Still’s Disease, ARDS..