Delayed Positivization of Cerebral Angiography in Reversible Cerebral
Vasoconstriction Syndrome (RCVS) Presenting with Recurrent Subarachnoid
Haemorrhage

Quartuccio, Luca; Tuniz, Francesco; Petralia, Benedetto; Zanotti, Bruno; Skrap, Miran; De Vita, Salvatore

Delayed Positivization of Cerebral Angiography in Reversible Cerebral Vasoconstriction Syndrome (RCVS) Presenting with Recurrent Subarachnoid Haemorrhage

Luca Quartuccio^{*, 1, §}, Francesco Tuniz^{2, §}, Benedetto Petralia³, Bruno Zanotti², Miran Skrap², Salvatore De Vita¹

¹ Clinic of Rheumatology, Azienda Ospedaliero-Universitaria di Udine, DSMB, Italy

² Department of Neurosurgery, Azienda Ospedaliero-Universitaria di Udine, Italy

³ Department of Neuroradiology, Azienda Ospedaliero-Universitaria di Udine, Italy

Article Information

Identifiers and Pagination:

Year: 2012
Volume: 6
First Page: 175
Last Page: 179
Publisher ID: TORJ-6-175
DOI: 10.2174/1874312901206010175

Article History:

Received Date: 21/5/2012
Revision Received Date: 15/6/2012
Acceptance Date: 25/6/2012
Electronic publication date: 25/7/2012
Collection year: 2012

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© Quartuccio et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

^* Address correspondence to this author at the Clinic of Rheumatology, DSMB, University of Udine, Univerisyt Hospital “Santa Maria della Misericordia”, Udine, Piazzale Santa Maria della Misericordia, 15, Italy; Tel: 0039 0432 559352; Fax: 0039 0432 559472; E-mail: quartuccio.luca@aoud.sanita.fvg.it
^§ L. Quartuccio and F. Tuniz equally collaborated to this work.

Benign angiopathy of the central nervous system is a clinical syndrome with evidence of reversible cerebral vasoconstriction (RCVS). Haemorrhagic stroke, either subarachnoid or intracerebral is an unusual presentation of RCVS. We describe a case of RCVS presenting with a subarachnoid haemorrhage (SAH), with rebleeding and onset of hydrocephalus during the first week, and, notably, delayed evidence of typical angiographic features after two negative prior exams. Normalization of the angiographic vasculitic-like lesions was documented at month +6. Repeated cerebral angiograms are mandatory to exclude this kind of disease, and the uncommon presentation of this case reinforces this concept.

Keywords: Reversible cerebral vasoconstriction syndrome, angiography, hydrocephalus, subarachnoid haemorrhage, vasculitis..

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RESEARCH ARTICLE

Delayed Positivization of Cerebral Angiography in Reversible Cerebral Vasoconstriction Syndrome (RCVS) Presenting with Recurrent Subarachnoid Haemorrhage

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