An Unusual Mimicker of Systemic Lupus Erythematosus: A Case Report

Aloice O Aluoch, Mathew Farbman, Heather Gladue*
Department of Medicine, Division of Rheumatology, Emory University, Atlanta, GA 30322, USA

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© Aluoch et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Medicine, Division of Rheumatology, Emory University, Atlanta, 1365 Clifton Rd. NE, Building A, 4th Floor, Atlanta, GA 30322, USA; Tel: 404-778-4366; Fax: 404-778-3217; E-mail:


We present a case of a 47 year-old African American female with 15 pack-years of tobacco use and heavy alcohol use who presented with arthritis and was found to have a positive antinuclear antibodies (ANA), anti double stranded DNA antibodies (anti-dsDNA), and anti-Sjogren’s syndrome-related antigen A and antigen B (anti-SSA and anti-SSB). She was subsequently found to have a lung adenocarcinoma associated with hypertrophic pulmonary osteoarthropathy (HPO). This demonstrates a case of positive antinuclear antibodies and arthritis in a patient with lung adenocarcinoma, which can be falsely diagnosed as systemic lupus erythematosus.

Keywords: Adenocarcinoma, antibodies, hypertrophic osteoarthropathy, systemic lupus erythematosus.